COVAXIN ( BHARAT BIOTECH)
COVAXIN, India's homegrown COVID-19 vaccine by Bharat Biotech is developed in collaboration with the Indian Council of Medical Research (ICMR) - National Institute of Virology (NV) .The indigenous, inactivated vaccine is developed and manufactured in Bharat Biotech's BSL-3 (Bio-Safety Level 3) high containment facility.The vaccine is developed using Whole-Virion Inactivated Vero Cell derived platform technology. Inactivated vaccines do not replicate and are therefore unlikely to revert and cause pathological effects. They contain dead virus, incapable of infecting people but still able to instruct the immune system to mount a defensive reaction against an infection. Conventionally, inactivated vaccines have been around for decades. Numerous vaccines for diseases such as Seasonal Influenza, Polio, Pertussis, Rabies, and Japanese Encephalitis use the same technology to develop inactivated vaccines with a safe track record of >300 million doses of supplies to date. It is the well-established, and time-tested platform in the world of vaccine technology.
KEY POINT :
💥COVAXIN is included along with immune-potentiators, also known as vaccine adjuvants, which are added to the vaccine to increase and boost its immunogenicity.
💥 It is a 2-dose vaccination regimen given 28 days apart.
💥 It is a vaccine with no sub-zero storage, no reconstitution requirement, and ready to use liquid presentation in multi-dose vials, stable at 2-8oC.
💥 Pre-clinical studies: Demonstrated strong immunogenicity and protective efficacy in animal challenge studies conducted in hamsters & non-human primates. For more information about our animal study, please visit our blog page on Non-Human Primates.
💥 The vaccine received DCGI approval for Phase I & II Human Clinical Trials in July, 2020.
COVISHIELD(SERUM INSTITUTE OF INDIA)
COVISHIELD,It is a UK based vaccine which named AstraZeneca discovered by Oxford universty.it was clinically approved by govt. of India. Covishield is based on viral vector platform. A chimpanzee adenovirus called ChAdOx1 is the vector that has been modified to carry the corona virus spike protein into human cells. The adenovirus vector platform for vaccine gained traction during the battle to stop Ebola. SII(Serum institute of India) is approved for people aged 18 year and above. Pune based Serum institute manufactured the Covishield. Now in India its price is 250- 400 Rupees estimated by Indian Govt.
KEY POINT: 💥 It is rapidly boost the immunity system in body. 💥 It is a 2 dose vaccination system given 84 day apart. 💥 It is also stored in the Temp of 2-8 degree celcius.